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The Ins and Outs of Clusterin: Its Role in Cancer, Eye Diseases and Wound Healing

24 Aug 2023

Abstract excerpt

Clusterin (CLU) is a glycoprotein originally discovered in 1983 in ram testis fluid. Rapidly observed in other tissues, it was initially given various names based on its function in different tissues. In 1992, it was finally named CLU by consensus. Nearly omnipresent in human tissues, CLU is strongly expressed at fluid–tissue interfaces, including in the eye and in particular the cornea. Recent research has...

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PMID: 37685987
DOI: 10.3390/ijms241713182

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