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Clusterin: a double-edged sword in cancer and neurological disorders

10 May 2024

Abstract excerpt

Clusterin is a ubiquitously expressed glycoprotein that is involved in a whole range of biological processes. This protein is known to promote tumor survival and resistance to therapy in cancer, which contrasts sharply with its neuroprotective functions in various neurological diseases. This duality has led to recent investigations into the potential therapeutic applications of clusterin inhibition, particularly...

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PMID: 39253532
DOI: 10.17179/excli2024-7369

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