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Polycystic ovary syndrome and epithelial-mesenchymal transition: Mendelian randomization and single-cell analysis insights

19 Feb 2025

Abstract excerpt

BACKGROUND: The process of epithelial-mesenchymal transition (EMT) may promote fibrosis in ovarian tissue related to polycystic ovary syndrome (PCOS), thus affecting ovarian function and hormonal balance. OBJECTIVE: This study aimed to explore key genes associated with EMT in PCOS and their potential molecular regulatory mechanisms, exclusively from the perspective of transcriptomics and single-cell RNA...

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Share to Ovarian function and disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39972362
DOI: 10.1186/s13048-025-01617-2

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