Acceptability and somatic mutations in cervicovaginal self-sampling for early endometrial cancer detection in women with Lynch syndrome.

doi:10.1002/ijc.35368

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Article

Acceptability and somatic mutations in cervicovaginal self-sampling for early endometrial cancer detection in women with Lynch syndrome.

International journal of cancer - 1 May 2025

Peremiquel-Trillas Paula, Martínez José Manuel, Paytubi Sònia, Frias-Gomez Jon, Pelegrina Beatriz, Marin Fátima, Benavente Yolanda, Ibáñez Raquel, Barahona Marc, Fernandez-Gonzalez Sergi, Cárdenas Laura, Taltavull Anna, Darder Esther, de Sanjosé Silvia, Widschwendter Martin, Matias-Guiu Xavier, Bosch Xavier, Pineda Marta, Ponce Jordi, Brunet Joan, Alemany Laia, Costas Laura

Abstract excerpt

New molecular approaches are being developed to detect endometrial cancer using minimally invasive sampling methods. This study aims to evaluate the acceptability of self-collected cervicovaginal samples among women with Lynch syndrome, a group at high risk for developing endometrial cancer. Participants collected cervicovaginal self-samples and answered an at-home acceptability questionnaire in a cross-sectional...

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PMID: 39952647
DOI: 10.1002/ijc.35368

Genes

ACVR2A
APC
ARID1A
KMT2D

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