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Article

Trajectories of Cortical Atrophy Differ According to Cognitive Phenotype in Adults With Primary Brain Tumors.

International journal of radiation oncology, biology, physics - 1 Jun 2025

Kohli Jiwandeep S, Reyes Anny, Hopper Austin, Stasenko Alena, Menendez Natalia, Tringale Kathryn R, Salans Mia, Karunamuni Roshan, Hattangadi-Gluth Jona, McDonald Carrie R

Abstract excerpt

PURPOSE: This study investigated patterns of cortical atrophy longitudinally in a prospective cohort of well-characterized patients with primary brain tumors before radiation therapy (RT) and at discrete time points up to 1-year post-RT. Patients with more impaired profiles were hypothesized to show greater and more widespread atrophy post-RT than patients with minimally impaired profiles. METHODS AND MATERIALS:...

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Identifiers

PMID: 39952441
DOI: 10.1016/j.ijrobp.2025.01.036
PMCID: PMC12777804

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