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Whole-exome sequencing identifies distinct genomic aberrations in eccrine porocarcinomas and poromas

13 Feb 2025

Abstract excerpt

BACKGROUND: Eccrine porocarcinoma (EPC) is a rare malignant skin tumor arising from the eccrine gland. Investigations into the genomic landscape of EPC have uncovered potential drivers of its development and progression. However, there is limited information on the discrepancies between EPC and its benign counterpart, eccrine poroma (EP). METHODS: Formalin-fixed paraffin-embedded (FFPE) samples from 15 EPCs and 5...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39948683
DOI: 10.1186/s13023-025-03586-7

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