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Article

Causal association between polyunsaturated fatty acids and acne: a two-sample Mendelian randomization study.

The British journal of dermatology - 19 May 2025

Kim Bo Ri, Kim Gahyun, Jin Seon-Pil, Choi Chong Won, Kim Jinho, Park Hyunsun

Abstract excerpt

BACKGROUND: Observational studies have demonstrated a close association between polyunsaturated fatty acids (PUFAs) and acne. However, the findings of clinical trials have been inconsistent, leaving the causal relationship between PUFAs and acne unclear. OBJECTIVES: To investigate the causal association between genetically proxied PUFAs and acne risk. METHODS: Mendelian randomization (MR) was performed using...

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PMID: 39936505
DOI: 10.1093/bjd/ljaf052

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FADS1

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