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Innovative application of ceftriaxone as a quorum sensing inhibitor in Pseudomonas aeruginosa

11 Feb 2025

Abstract excerpt

Pseudomonas aeruginosa is a Gram-negative bacterium that has the potential to induce various healthcare-related infections through its array of virulence factors. The control of virulence factor expression is mainly regulated by a communication process among cells called quorum sensing (QS). Blocking QS could be a viable tactic to suppress virulence factors and reduce pathogenicity without impacting bacterial...

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PMID: 39934154
DOI: 10.1038/s41598-025-87609-0

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