Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prenatal alcohol exposure is associated with altered feto-placental blood flow and sex-specific placental changes

10 Feb 2025

Abstract excerpt

BACKGROUNDPrenatal alcohol exposure (PAE) around conception in preclinical models results in placental insufficiency, likely contributing to offspring abnormalities. Altered placental DNA methylation (DNAm) and gene expression suggest epigenetic mechanisms, perhaps involving impacts on methyl donor levels. PAE around conception in women is common but placental effects are rarely examined. This cohort study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Pregnancy and preeclampsia studies
Share to Prenatal Substance Exposure Effects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39927463
DOI: 10.1172/jci.insight.186096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prenatal alcohol exposure is associated with altered feto-placental blood flow and sex-specific placental changesPMID 39927463Read ↗

Human placental methylome in the interplay of adverse placental health, environmental exposure, and pregnancy outcomeSemantic proximity Read ↗

Periconceptional alcohol exposure causes female-specific perturbations to trophoblast differentiation and placental formation in the ratSemantic proximity Read ↗

Early Peri-conceptional Alcohol Exposure before Implantation Disrupts Placental Development across GestationSemantic proximity Read ↗

Sex differences in DNA methylation across gestation: a large scale, cross-cohort, multi-tissue analysisSemantic proximity Read ↗

SExual Epigenetic Dimorphism in The Human Placenta: Implications for Susceptibility During The Prenatal PeriodSemantic proximity Read ↗

Early moderate prenatal alcohol exposure and maternal diet impact offspring DNA methylation across speciesSemantic proximity Read ↗

The placental exposome, placental epigenetic adaptations and lifelong cardio-metabolic healthSemantic proximity Read ↗

The influence of early environment and micronutrient availability on developmental epigenetic programming: lessons from the placentaSemantic proximity Read ↗

Maternal Choline Supplementation during Normal Murine Pregnancy Alters the Placental Epigenome: Results of an Exploratory Study.Semantic proximity Read ↗

An Update on Fetal Alcohol Syndrome—Pathogenesis, Risks, and TreatmentSemantic proximity Read ↗

Fetal Alcohol ExposureSemantic proximity Read ↗

Nonconceptus Mechanisms of Prenatal Alcohol Exposure That Disrupt Embryo-Fetal Development: An Integrative ViewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.