Article
Transcriptional dysregulation of autophagy in the muscle of a mouse model of Duchenne muscular dystrophy
16 Jan 2024
Abstract excerpt
It has been reported that autophagic activity is disturbed in the skeletal muscles of dystrophin-deficient mdx mice and patients with Duchenne muscular dystrophy (DMD). Transcriptional regulations of autophagy by FoxO transcription factors (FoxOs) and transcription factor EB (TFEB) play critical roles in adaptation to cellular stress conditions. Here, we investigated whether autophagic activity is dysregulated at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
