Article
Maternal dietary fatty acid composition and content prior to and during pregnancy and lactation influences serum profile, liver phenotype and hepatic miRNA expression in young male and female offspring.
The Journal of nutritional biochemistry - 1 Jul 2024
Mennitti Laís Vales, de Souza Esther Alves, Santamarina Aline Boveto, Sertorio Marcela Nascimento, Jucá Andrea, De Souza Daniel Vitor, Ribeiro Daniel Araki, Pisani Luciana Pellegrini
Abstract excerpt
This study aimed to investigate whether modifying the pre-gestational lipid content could mitigate metabolic damage in offspring from dams exposed to a high-fat (HF) diet before conception and during pregnancy and lactation, with a focus on sex-specific outcomes. Specific effects of maternal normolipidic diets on offspring were also assessed. Female Wistar rats received control (C) or HF diets before conception....
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