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Staphylococcus aureus induces mitophagy via the HDAC11/IL10 pathway to sustain intracellular survival

4 Feb 2025

Abstract excerpt

BACKGROUND: The immune evasion and prolonged survival of Staphylococcus aureus (S. aureus) within macrophages are key factors contributing to the difficulty in curing osteomyelitis. Although macrophages play a vital role as innate immune cells, the mechanisms by which S. aureus survives within them and suppresses host immune functions remain incompletely understood. METHODS: This study employed confocal...

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PMID: 39905391
DOI: 10.1186/s12967-025-06161-7

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