Article
Non-invasive diagnosis for urothelial carcinoma using a dual-target DNA methylation biomarker panel
26 Jan 2025
Abstract excerpt
BACKGROUND: Urothelial carcinoma (UC) is a common malignancy worldwide. Aberrant DNA methylation is implicated in UC carcinogenesis. This study sought to delineate the DNA methylation landscape in UC and identify DNA methylation-based biomarkers for early detection of UC. METHODS: Whole genome bisulfite sequencing (WGBS) was conducted on bladder cancer tissues and paired normal tissues. By integrating WGBS data...
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