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Article

Phosphorylated-tau associates with HSV-1 chromatin and correlates with nuclear speckles decondensation in low-density host chromatin regions

14 Jan 2025

Abstract excerpt

Abnormal tau phosphorylation is a key mechanism in neurodegenerative diseases . Evidence implicates infectious agents, such as Herpes Simplex Virus 1 (HSV-1), as co-factors in the onset or the progression of neurodegenerative diseases , including Alzheimer's disease . This has led to divergence in the field regarding the contribution of viruses in the etiology of neurodegenerative diseases. Research indicates...

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PMID: 39818277
DOI: 10.1016/j.nbd.2025.106804

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Phosphorylated-tau associates with HSV-1 chromatin and correlates with nuclear speckles decondensation in low-density host chromatin regionsPMID 39818277Read ↗

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