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The Hippo Signaling Pathway Manipulates Cellular Senescence

26 Dec 2024

Abstract excerpt

The Hippo pathway, a kinase cascade, coordinates with many intracellular signals and mediates the regulation of the activities of various downstream transcription factors and their coactivators to maintain homeostasis. Therefore, the aberrant activation of the Hippo pathway and its associated molecules imposes significant stress on tissues and cells, leading to cancer, immune disorders, and a number of diseases....

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PMID: 39791714
DOI: 10.3390/cells14010013

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