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Article

Presymptomatic Identification of Cancers in Pregnant Women During Noninvasive Prenatal Testing.

JAMA oncology - 1 Sept 2015

Amant Frédéric, Verheecke Magali, Wlodarska Iwona, Dehaspe Luc, Brady Paul, Brison Nathalie, Van Den Bogaert Kris, Dierickx Daan, Vandecaveye Vincent, Tousseyn Thomas, Moerman Philippe, Vanderstichele Adriaan, Vergote Ignace, Neven Patrick, Berteloot Patrick, Putseys Katrien, Danneels Lode, Vandenberghe Peter, Legius Eric, Vermeesch Joris Robert

Abstract excerpt

IMPORTANCE: Noninvasive prenatal testing (NIPT) for fetal aneuploidy by scanning cell-free fetal DNA in maternal plasma is rapidly becoming a major prenatal genetic test. Similar to placental DNA, tumor DNA can be detected in the plasma, and analysis of cell-free tumor DNA can be used to characterize and monitor cancers. We show that plasma DNA profiling allows for presymptomatic detection of tumors in pregnant...

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Identifiers

PMID: 26355862
DOI: 10.1001/jamaoncol.2015.1883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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