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Article

Maternal Malignancy After Atypical Findings on Single-Nucleotide Polymorphism-Based Prenatal Cell-Free DNA Screening.

Obstetrics and gynecology - 1 Apr 2023

Goldring Georgina, Trotter Cindy, Meltzer Jeffrey T, Souter Vivienne, Pais Lynn, DiNonno Wendy, Xu Wenbo, Weitzel Jeffrey N, Vora Neeta L

Abstract excerpt

OBJECTIVE: To evaluate the incidence and clinical outcomes of cell-free DNA results suspicious for maternal malignancy on prenatal cell-free DNA screening with single-nucleotide polymorphism (SNP)-based technology. METHODS: This retrospective cohort study included data from SNP-based, noninvasive prenatal screening samples from a commercial laboratory from January 2015 to October 2021. Maternal plasma was...

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PMID: 36897127
DOI: 10.1097/AOG.0000000000005107
PMCID: PMC10026947

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