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Prenatal cell-free DNA testing of women with pregnancy-associated cancer: a retrospective cross-sectional study

7 Aug 2024

Abstract excerpt

Background: Incidentally, the non-invasive prenatal test (NIPT) shows chromosomal aberrations suspicious of a maternal malignancy, especially after genome-wide testing. The aim of this study is to determine how many cases of cancer in pregnancy are diagnosed or missed with NIPT and whether in retrospect subtle changes in NIPT results could have detected cancer. Methods: We identified Dutch patients diagnosed in...

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PMID: 39220433
DOI: 10.1016/j.lanepe.2024.101024

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