Article
Genetic Variations on Chromosome 6p21 Are Associated with Asthma Risk and Disease Severity: A Case-Control Study from Pakistan.
Genes - 17 Dec 2024
Aslam Aqsa, Vijverberg Susanne J H, Zee Anke-Hilse Maitland-van der, Sabar Muhammad Farooq
Abstract excerpt
BACKGROUND: Genetic factors play a role in asthma severity. However, low- and middle-income countries have minimal contribution to genomic asthma research. The current study investigates the influence of an important genetic asthma region (6p21) on severe asthma in a cohort of asthmatics in Pakistan. MATERIALS AND METHODS: In this case-control study, mild to severe asthmatic patients (n = 255) and controls (n =...
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