Article
Major histocompatibility complex class II polymorphic variants are associated with asthma predisposition in the Punjabi population of Lahore, Pakistan.
The clinical respiratory journal - 1 Apr 2021
Aslam Raheela, Shahid Mariam, Bano Iqbal, Ayoub Muhammad, Sabar Muhammad Farooq, Altaf Saba, Kousar Samra, Ghani Muhammad Usman, Husnain Tayyab, Shahid Ahmad Ali
Abstract excerpt
INTRODUCTION: Various genome wide association studies have manifested that Major Histocompatibility Complex (MHC) region on chromosome 6p21 houses many potential candidate genes for asthma. OBJECTIVE: This Case-Control association study was planned to determine the association of 10 Single Nucleotide Polymorphisms (SNPs), residing within and around MHC genes' region on chromosome 6p21, with Asthma in Punjabi...
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