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Article

Genetic predisposition of metabolic dysfunction-associated steatotic liver disease: a population-based genome-wide association study.

Hepatology international - 1 Apr 2025

Wang Shao-Wen, Wang Ching, Cheng Yu-Ming, Chen Chun-Yi, Hsieh Tsung-Han, Wang Chia-Chi, Kao Jia-Horng

Abstract excerpt

BACKGROUND/PURPOSE: Although metabolic dysfunction-associated steatotic liver disease (MASLD) has been proposed to replace the diagnosis of non-alcoholic fatty liver disease (NAFLD) with new diagnostic criteria since 2023, the genetic predisposition of MASLD remains to be explored. METHODS: Participants with data of genome-wide association studies (GWAS) in the Taiwan Biobank database were collected. Patients...

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Identifiers

PMID: 39755997
DOI: 10.1007/s12072-024-10769-0

Genes

SAMM50
PNPLA3

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