Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pan-cancer analysis reveals the oncogenic and immunomodulatory roles of PTGFRN across human cancers.

Scientific reports - 27 Feb 2026

Mu Nan, Dong Tianjian, Sheng Qingyu, Duan Zhuoning, Wang Xiangming, Zhao Qi

Abstract excerpt

The role of the prostaglandin F2 receptor negative regulator (PTGFRN) in tumor biology remains incompletely understood. This study aimed to perform a comprehensive pan-cancer analysis to elucidate the functions of PTGFRN in tumor progression and its potential immunomodulatory effects. Utilizing data from the cancer genome atlas (TCGA) and the genotype-tissue expression (GTEx) project, we analyzed PTGFRN...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Gene Expression Regulation, Neoplastic

Share to Mutation

Share to Neoplasms

Share to Prognosis

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 41748870
DOI: 10.1038/s41598-026-41027-y
PMCID: PMC13049031

Genes

PTGFRN
F2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pan-cancer analysis reveals the oncogenic and immunomodulatory roles of PTGFRN across human cancers.PMID 41748870Read ↗

An integrated pan-cancer analysis of TFAP4 aberrations and the potential clinical implications for cancer immunity.Semantic proximity Read ↗

The potential of FCRL genes as targets for cancer treatment: insights from bioinformatics and immunology.Semantic proximity Read ↗

Pan-cancer analysis reveals potential of RRM2 as a prognostic and immunological biomarker in human cancerSemantic proximity Read ↗

RNF24 is a Novel Biomarker of Prognosis and Immunological Cell Infiltration in CancersSemantic proximity Read ↗

Analysis of the correlation between the expression of non-classical E2F transcription factor 8 (E2F8) in pan-cancer and prognosis and immune infiltrationSemantic proximity Read ↗

Identifying the oncogenic roles of FAP in human cancers based on systematic analysisSemantic proximity Read ↗

CENPF Upregulation is Associated with Immunosuppressive Status and Predicts Poor Clinical Outcomes in Lung Adenocarcinoma Validated by Qrt- PCRSemantic proximity Read ↗

A comprehensive pan-cancer examination of transcription factor MAFF: Oncogenic potential, prognostic relevance, and immune landscape dynamicsSemantic proximity Read ↗

ARNTL2, an Immunoregulation-Related Prognostic Biomarker in Pan-Cancer and Lung AdenocarcinomaSemantic proximity Read ↗

Comprehensive pan-cancer analysis reveals NTN1 as an Immune infiltrate risk factor and its potential prognostic value in SKCMSemantic proximity Read ↗

IRF4 instructs effector Treg differentiation and immune suppression in human cancerSemantic proximity Read ↗

Pan-cancer analysis of DEFB1 as a candidate prognostic biomarker and associated with immune infiltrationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.