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[Analysis of ASXL1 gene variant in patients with myelodysplastic syndrome].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Feb 2020

Chen Meiyu, Liu Jie, Chao Hongying, Qin Wei, Jiang Naike, Lu Xuzhang, Cen Ling, Jiang Yu, Cai Xiaohui, Zhang Ri, Wang Qian

Abstract excerpt

OBJECTIVE: To detect ASXL1 gene variants among patients with myelodysplastic syndrome (MDS) and explore their correlation with variants of other genes and clinical features of patients. METHODS: For 149 patients with MDS, genomic DNA was amplified by PCR and subject to direct sequencing to identify variants of ASXL1, U2AF1, SF3B1, DNMT3A, TET2, IDH1/2, NPM1, FLT3-ITD and C-KIT genes. RESULTS: ASXL1 variants were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32034733
DOI: 10.3760/cma.j.issn.1003-9406.2020.02.003

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