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The Ku protein family regulates hyperglycemia-induced vascular endothelial cell inflammation by modulating P300 levels

30 Dec 2024

Abstract excerpt

Endothelial inflammation caused by hyperglycemia contributes to cardiovascular complications in patients with diabetes. Diabetic kidney injury (DKI) is one of the most significant manifestations of diabetes-related renal damage, encompassing both acute and early chronic kidney injury. DKI involves pathological mechanisms linked to inflammatory responses and early renal damage, which, if left unchecked, may...

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PMID: 39743014
DOI: 10.1016/j.yexcr.2024.114399

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