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Article

The Role of Histone Modifications in the Pathogenesis of Diabetic Kidney Disease

22 Mar 2023

Abstract excerpt

Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease. The pathogenesis of DKD is multifactorial, with several molecular pathways implicated. Recent data suggest that histone modification plays an important role in the development and progression of DKD. Histone modification appears to induce oxidative stress, inflammation and fibrosis in the diabetic kidney. In the present review, we...

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Share to Adenosine and Purinergic Signaling
Share to Chronic Kidney Disease and Diabetes
Share to Epigenetics and DNA Methylation

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PMID: 36983082
DOI: 10.3390/ijms24066007

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