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Genomic instability-derived plasma extracellular vesicle-microRNA signature as a minimally invasive predictor of risk and unfavorable prognosis in breast cancer

12 Jan 2021

Abstract excerpt

BACKGROUND: Breast cancer (BC) is the most frequently diagnosed cancer and the leading cause of cancer-associated deaths in women. Recent studies have indicated that microRNA (miRNA) regulation in genomic instability (GI) is associated with disease risk and clinical outcome. Herein, we aimed to identify the GI-derived miRNA signature in extracellular vesicles (EVs) as a minimally invasive biomarker for early...

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Biomarkers in Disease Mechanisms
Extracellular vesicles in disease
Ferroptosis and cancer prognosis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33436002
DOI: 10.1186/s12951-020-00767-3

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