Identification and verification of ferroptosis-related genes in the synovial tissue of osteoarthritis using bioinformatics analysis

Abstract excerpt

Background: Osteoarthritis (OA) is a major factor causing pain and disability. Studies performed to date have suggested that synovitis is possibly a critical OA-related pathological change. Ferroptosis represents a novel type of lipid peroxidation-induced iron-dependent cell death. However, its effect on OA remains largely unclear. Objective: This work focused on identifying and validating the possible...

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