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Article

Development and validation of a radiomics nomogram for preoperative prediction of BRAFV600E mutation status in adult patients with craniopharyngioma.

Neurosurgical review - 27 Dec 2024

Qiao Ning, Li Chuzhong, Zheng Fei, Zhang Lingling, Ma Guofo, Jia Yanfei, Cai Kefan, Chen Xuzhu, Lu Pengwei, Zhang Yazhuo, Gui Songbai

Abstract excerpt

Although craniopharyngiomas are rare benign brain tumors primarily managed by surgery, they are often burdened by a poor prognosis due to tumor recurrence and long-term morbidity. In recent years, BRAFV600E-targeted therapy has been promising, showing potential as an adjuvant or neoadjuvant approach. Therefore, we aim to develop and validate a radiomics nomogram for preoperative prediction of BRAFV600E mutation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39729136
DOI: 10.1007/s10143-024-03170-w

Genes

BRAF

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