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Article

Uremic Toxin-Producing Gut Microbiota in Rats with Chronic Kidney Disease

4 Oct 2016

Abstract excerpt

BACKGROUND: In patients with chronic kidney disease (CKD), many metabolites of gut microbiota retain in the body as uremic toxins (UTs). However, the kinds of bacteria producing UTs are rarely discussed. METHODS: We analyzed UT production and the composition of gut microbiota in CKD rats and cecectomized rats. AST-120, a spherical carbon adsorbent, was administrated to evaluate how the precursors of UT affect gut...

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PMID: 27701177
DOI: 10.1159/000450619

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