Article
First genome-wide association study investigating blood pressure and renal traits in domestic cats.
Scientific reports - 3 Feb 2022
Jepson R E, Warren H, Wallace M D, Syme H M, Elliott J, Munroe P B
Abstract excerpt
Hypertension (HTN) and chronic kidney disease (CKD) are common in ageing cats. In humans, blood pressure (BP) and renal function are complex heritable traits. We performed the first feline genome-wide association study (GWAS) of quantitative traits systolic BP and creatinine and binary outcomes HTN and CKD, testing 1022 domestic cats with a discovery, replication and meta-analysis design. No variants reached...
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