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A mechanistic, functional, and clinical perspective on targeting CD70 in cancer

24 Dec 2024

Abstract excerpt

The oncoimmunology research has witnessed notable advancements in recent years. Reshaping the tumor microenvironment (TME) approach is an effective method to improve antitumor immune response. The T cell-mediated antitumor response is crucial for favorable therapeutic outcomes in several cancers. The United States Food and Drug Administration (FDA) has approved immune checkpoint inhibitors (ICIs) for targeting...

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PMID: 39725151
DOI: 10.1016/j.canlet.2024.217428

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