A pathway-based genetic score for inflammation: An indicator of vulnerability to phthalate-induced adverse neurodevelopment outcomes.

doi:10.1016/j.ijheh.2024.114514

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A pathway-based genetic score for inflammation: An indicator of vulnerability to phthalate-induced adverse neurodevelopment outcomes.

International journal of hygiene and environmental health - 1 Mar 2025

Elagali Ahmed, Eisner Alex, Tanner Samuel, Drummond Katherine, Symeonides Christos, Love Chloe, Tang Mimi Lk, Mansell Toby, Burgner David, Collier Fiona, Sly Peter D, O'Hely Martin, Dunlop Sarah, Vuillermin Peter, Ponsonby Anne-Louise

Abstract excerpt

INTRODUCTION: Phthalates, chemical additives used to enhance plastic products' flexibility, are easily released into the environment, and can harm the brain development through various mechanisms including inflammation. Genetic variation influencing an individual's susceptibility to inflammation may play a role in the effects of phthalate exposure on neurodevelopment however there is no summary measure developed...

Read the complete abstract on PubMed

Topics

Humans
Phthalic Acids
Female
Male
Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Inflammation

Pregnancy

Genetic Predisposition to Disease

Environmental Pollutants

Autism Spectrum Disorder

Prenatal Exposure Delayed Effects

Attention Deficit Disorder with Hyperactivity

Neurodevelopmental Disorders

Infant

Environmental Exposure

Source

Open in PubMed

Identifiers

PMID: 39721371
DOI: 10.1016/j.ijheh.2024.114514

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A pathway-based genetic score for inflammation: An indicator of vulnerability to phthalate-induced adverse neurodevelopment outcomes.PMID 39721371Read ↗

Prenatal phthalate exposure, oxidative stress-related genetic vulnerability and early life neurodevelopment: A birth cohort study.Semantic proximity Read ↗

Environmental pollutants and autism spectrum disorder: Effects of plasticizers on core phenotypes and molecular targets.Semantic proximity Read ↗

Prenatal and postnatal exposure to PFAS and cardiometabolic factors and inflammation status in children from six European cohortsSemantic proximity Read ↗

Cytokines as mediators of the associations of prenatal exposure to phenols, parabens, and phthalates with internalizing behaviours at age 3 in boys: a mixture exposure and mediation approachSemantic proximity Read ↗

Common genetic variants associated with urinary phthalate levels in children: a genome-wide studySemantic proximity Read ↗

Prenatal DEHP exposure predicts neurological disorders via transgenerational epigeneticsSemantic proximity Read ↗

Common genetic variants associated with urinary phthalate levels in children: A genome-wide study.Semantic proximity Read ↗

Prenatal inflammation and neurodevelopment in schizophrenia: A review of human studiesSemantic proximity Read ↗

Exposures to perfluoroalkyl substances and asthma phenotypes in childhood: an investigation of the COPSAC2010 cohort.Semantic proximity Read ↗

Neonatal urinary phthalate metabolite concentrations predict the development of atopic dermatitisSemantic proximity Read ↗

Placental-brain axis in females detected within broadly impacted metabolic gene networks protects against prenatal PCB exposureSemantic proximity Read ↗

Association Studies of Environmental Exposures, DNA Methylation and Children’s Cognitive, Behavioral, and Mental Health ProblemsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.