Article
Case report: Therapeutic response of front-line cadonilimab plus chemotherapy on patient with advanced lung adenocarcinoma harboring STK11 genetic aberration.
Frontiers in immunology - 1 Jan 2024
Feng Du, Jiang Huixin, Chen Gengjia, Guan Wenhui, Yi Lin, Zhu Yue, Li Yijia, Huang Gengda, He Bin, Tang Junlong, Tang Yujie, Zeng Jiyuan, Zhou Wensheng, Shi Jiayu, Xie Zhanhong, Liu Ming, Xie Xiaohong, Lin Xinqing, Zhou Chengzhi
Abstract excerpt
The STK11 gene mutation is a common genetic alteration in non-small cell lung cancer (NSCLC) and is significantly associated with poor responses to current immunotherapy regimens. Despite its prevalence, there is currently no established standard for front-line treatment in this subtype of NSCLC, underscoring the increasing need for personalized therapeutic strategies. In this report, we present a case of a...
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