Article
Carbamazepine metabolism in man. Induction and pharmacogenetic aspects.
Clinical pharmacokinetics - 1 Jan 2000
Eichelbaum M, Tomson T, Tybring G, Bertilsson L
Abstract excerpt
The metabolism of carbamazepine (CBZ) was studied in 3 groups of subjects: (1) 6 healthy volunteers given a single dose of 200mg carbamazepine; (2) 4 epileptic patients on carbamazepine monotherapy; and (3) 5 patients receiving carbamazepine in combination with other anticonvulsants. Carbamazepin...
Topics
- Adult
- Biotransformation
- Carbamazepine
- Female
- Half-Life
- Humans
- Kinetics
- Male
- Phenotype