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Article

Can CT-based radiomics signature predict KRAS/NRAS/BRAF mutations in colorectal cancer?

European radiology - 1 May 2018

Yang Lei, Dong Di, Fang Mengjie, Zhu Yongbei, Zang Yali, Liu Zhenyu, Zhang Hongmei, Ying Jianming, Zhao Xinming, Tian Jie

Abstract excerpt

OBJECTIVES: To investigate whether CT-based radiomics signature can predict KRAS/NRAS/BRAF mutations in colorectal cancer (CRC). METHODS: This retrospective study consisted of a primary cohort (n = 61) and a validation cohort (n = 56) with pathologically confirmed CRC. Patients underwent KRAS/NRAS/BRAF mutation tests and contrast-enhanced CT before treatment. A total of 346 radiomics features were extracted from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29335867
DOI: 10.1007/s00330-017-5146-8

Genes

BRAF
KRAS
NRAS

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