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Article

Preoperative prediction of KRAS mutation status in colorectal cancer using a CT-based radiomics nomogram.

The British journal of radiology - 1 Jun 2022

Xue Ting, Peng Hui, Chen Qiaoling, Li Manman, Duan Shaofeng, Feng Feng

Abstract excerpt

OBJECTIVE: This study aimed to develop a model to predict KRAS mutations in colorectal cancer according to radiomic signatures based on CT and clinical risk factors. METHODS: This retrospective study included 172 patients with colorectal cancer. All patients were randomized at a 7:3 ratio into a training cohort (n = 121, 38.8% positive for KRAS mutation) and a validation cohort (n = 51, 39.2% positive for KRAS...

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Identifiers

PMID: 35312376
DOI: 10.1259/bjr.20211014
PMCID: PMC10996413

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