Article
Sarcomatous transformation of IDH-mutant astrocytoma matching to methylation class oligosarcoma following embolization, a case report.
Acta neuropathologica communications - 20 Dec 2024
Landvater Ryan, Tripathy Arushi, Nieblas-Bedolla Edwin, Shao Lina, Conway Kyle, Al-Holou Wajd, Ferris Sean P
Abstract excerpt
The mesenchymal transformations of infiltrating gliomas are uncommon events. This is particularly true of IDH-mutant astrocytomas and oligodendrogliomas, in which mesenchymal transformation is exceedingly rare. oligosarcoma is a newly recognized methylation class (MC) that represents transformed 1p/19q co-deleted oligodendrogliomas, but recent studies indicate it may be non-specific. Herein we report the diffuse...
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