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AMPK-mTOR pathway modulates glycolysis reprogramming in unexplained recurrent spontaneous abortion

20 Dec 2024

Abstract excerpt

Recurrent spontaneous abortion (RSA), whose underlying cause has yet to be fully elucidated, is often classified as unexplained recurrent spontaneous abortion (URSA). Promoting the differentiation of CD4 + T cells into Tregs may be the key to prevent URSA. The differentiation of CD4 + T cells was controlled by mTOR, but the regulatory mechanism is still unclear. This study aims to explore the regulatory role of...

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PMID: 39707242
DOI: 10.1186/s12884-024-07054-1

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