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Berberine promotes primordial follicle activation and increases ovulated oocyte quantity in aged mice

20 Dec 2024

Abstract excerpt

BACKGROUND: Primordial follicle activation is vital for the reproduction of women with advanced age and premature ovarian insufficiency (POI). But there is a lack of effective and safe therapeutic options to activate their primordial follicles in vivo. Berberine (BBR) possesses multiple pharmacological properties, but its impact on primordial follicle activation remains unclear. METHODS: The role of BBR on...

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PMID: 39707173
DOI: 10.1186/s10020-024-01042-z

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