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Article

Current mechanisms of primordial follicle activation and new strategies for fertility preservation

28 Jan 2021

Abstract excerpt

Premature ovarian insufficiency (POI) is characterized by symptoms caused by ovarian dysfunction in patients aged <40 years. It is associated with a shortened reproductive lifespan. The only effective treatment for patients who are eager to become pregnant is IVF/Embryo Transfer (ET) using oocytes donated by young women. However, the use of the technique is constrained by the limited supply of oocytes and ethical...

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PMID: 33538812
DOI: 10.1093/molehr/gaab005

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