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In vivo and in vitro activation of dormant primordial follicles by EGF treatment in mouse and human

1 Sept 2020

Abstract excerpt

In the mammalian ovaries, dormant primordial follicles represent the reproductive reserve of individual females. Recently, stimulating the activation of primordial follicles in vitro has been practiced, making the utilization of those dormant follicles to treat female infertility possible. However, there are still lacks of effective upstream molecule and strategy to elevate follicle activation in vivo. In the...

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PMID: 32997412
DOI: 10.1002/ctm2.182

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