Article
DICER1-Related Tumor Predisposition: Identification of At-risk Individuals and Recommended Surveillance Strategies.
Clinical cancer research : an official journal of the American Association for Cancer Research - 16 Dec 2024
Schultz Kris Ann P, Nelson Alexander T, Mallinger Paige H R, Harris Anne K, Kamihara Junne, Baldinger Shari, Chen Kenneth S, Pond Dinel, Hatton Jessica N, Dybvik Anna G, Mitchell Sarah G, Perrino Melissa R, Ben-Ami Tal, Kachanov Denis, Su Yan, Duan Chao, Olson Damon R, Watson Dave, Field Amanda L, Harney Laura A, Garrity Carr Ann, Frazier A Lindsay, Schneider Dominik T, Wilson David B, MacFarland Suzanne P, Schoettler Peter J, Bauer Andrew J, Dehner Louis P, Hill Dana Ashley, Stewart Douglas R, Messinger Yoav H
Abstract excerpt
PURPOSE: DICER1-related tumor predisposition increases risk for a spectrum of benign and malignant tumors. In 2018, the International Pleuropulmonary Blastoma (PPB)/DICER1 Registry published guidelines for testing- and imaging-based surveillance of individuals with a known or suspected germline DICER1 pathogenic or likely pathogenic (P/LP) variant. One of the goals of the Registry is to continue to refine these...
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