Article
Programmed Death Ligand 1 Expression and Related Markers in Pleuropulmonary Blastoma.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society - 1 Jan 2000
Alipour Zahra, Schultz Kris Ann P, Chen Ling, Harris Anne K, Gonzalez Ivan A, Pfeifer John, Hill D Ashley, He Mai, Dehner Louis P
Abstract excerpt
INTRODUCTION: Pleuropulmonary blastoma (PPB), a rare childhood neoplasm of the lung, is linked to pathogenic DICER1 variants. We investigated checkpoint inhibitor markers including Programmed Death Ligand 1 (PD-L1), PD1, CD8 and tumor mutational burden (TMB) in PPB. MATERIAL AND METHODS: Cases were collected from departmental archives and the International PPB/DICER1 Registry. Immunohistochemistry (IHC) for...
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