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ABALON regulates mitophagy and 5-FU sensitivity in colorectal cancer via PINK1-Parkin pathway

1 Nov 2024

Abstract excerpt

Background: Growing evidence demonstrated that long non-coding RNAs (lncRNAs) are closely related with chemoresistance in colorectal cancer (CRC). Mitophagy serves as an essential factor to maintain the quality of tumor cells. However, it is unclear whether lncRNAs are involved in mitophagy regulation in CRC. The aim of this study is to evaluate whether lncRNAs are involved in regulating mitophagy and...

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PMID: 39697760
DOI: 10.21037/tcr-24-933

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