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Article

LncRNAs as Regulators of Autophagy and Drug Resistance in Colorectal Cancer

2 Oct 2019

Abstract excerpt

Colorectal cancer (CRC) is a common malignancy with 1. 8 million cases in 2018. Autophagy helps to maintain an adequate cancer microenvironment in order to provide nutritional supplement under adverse conditions such as starvation and hypoxia. Additionally, most of the cases of CRC are unresponsive to chemotherapy, representing a significant challenge for cancer therapy. Recently, autophagy induced by therapy has...

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PMID: 31632922
DOI: 10.3389/fonc.2019.01008

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