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[Online phenotypes of depression symptoms are associated with polygenic risk scores of somatic diseases in a population-based cohort].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2024

Kibitov A O, Rakitko A S, Kasyanov E D, Rukavishnikov G V, Shumskaia D S, Ilinsky V V, Neznanov N G, Mazo G E

Abstract excerpt

OBJECTIVE: To test an associations of online phenotypes of depressive symptoms with polygenic risk scores (PRS) for selected somatic diseases in a population-based cohort. MATERIAL AND METHODS: Participants in a Russian population-based cohort (n=4520) underwent online phenotyping based on the originally developed questionnaire using DSM-5 criteria (DSM phenotypes) and the Hospital Anxiety and Depression Scale...

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PMID: 39690559
DOI: 10.17116/jnevro2024124111122

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