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Article

A Histone Deacetylase Complex Mediates Biofilm Dispersal and Drug Resistance in Candida albicans

11 Jun 2014

Abstract excerpt

UNLABELLED: Biofilms are resilient, surface-associated communities of cells with specialized properties (e.g., resistance to drugs and mechanical forces) that are distinct from those of suspension (planktonic) cultures. Biofilm formation by the opportunistic human fungal pathogen Candida albicans is medically relevant because C. albicans infections are highly correlated with implanted medical devices, which...

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PMID: 24917598
DOI: 10.1128/mbio.01201-14

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