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Identification of Ferroptosis‐Related Gene in Age‐Related Macular Degeneration Using Machine Learning

1 Dec 2024

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is a major cause of irreversible visual impairment, with dry AMD being the most prevalent form. Programmed cell death of retinal pigment epithelium (RPE) cells is a central mechanism in the pathogenesis of dry AMD. Ferroptosis, a recently identified form of programmed cell death, is characterized by iron accumulation-induced lipid peroxidation. This study aimed...

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PMID: 39679976
DOI: 10.1002/iid3.70059

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