Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Case report: A cyclic neutropenia patient with ELANE mutation accompanied by hemophagocytic lymphohistiocytosis.

Frontiers in immunology - 1 Jan 2024

Yu Lang, Li Yulin, Li Wenhui, Zhang Yishi, He Wenli, Tang Xuemei, An Yunfei, Zhao Xiaodong

Abstract excerpt

Many inborn errors of immunity may accompany secondary hemophagocytic lymphohistiocytosis (HLH), a condition typically characterized by impaired cytotoxic T and NK cell function. A considerable proportion of HLH cases also stem from chronic granulomatosis with phagocytic dysfunction. However, the development of secondary HLH in patients with severe congenital neutropenia (SCN) or cyclic neutropenia (CyN) with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Killer Cells, Natural
Share to Leukocyte Elastase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphohistiocytosis, Hemophagocytic

Share to Mutation

Share to Neutropenia

Source

Open in PubMed Open full text

Identifiers

PMID: 39676859
DOI: 10.3389/fimmu.2024.1474429
PMCID: PMC11638164

Genes

ELANE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Case report: A cyclic neutropenia patient with ELANE mutation accompanied by hemophagocytic lymphohistiocytosis.PMID 39676859Read ↗

Severe congenital neutropenia caused by ELANE gene mutation: A case report and literature review.Semantic proximity Read ↗

A case report of de novo ELANE c.416C>T mutation causing cyclic neutropenia in a 7-year-old girl.Semantic proximity Read ↗

Congenital and acquired neutropenia.Semantic proximity Read ↗

Impact of different genetic mutations on granulocyte development and G-CSF responsiveness in congenital neutropenia.Semantic proximity Read ↗

ELANE mutations in cyclic and severe congenital neutropenia: genetics and pathophysiology.Semantic proximity Read ↗

Spectrum of ELANE mutations in congenital neutropenia: a single-centre study in patients of Indian origin.Semantic proximity Read ↗

Screening for ELANE, HAX1 and GFI1 gene mutations in children with neutropenia and clinical characterization of two novel mutations in ELANE gene.Semantic proximity Read ↗

Discerning clinicopathological features of congenital neutropenia syndromes: an approach to diagnostically challenging differential diagnoses.Semantic proximity Read ↗

ELANE gene mutation-induced cyclic neutropenia manifesting as recurrent fever with oral mucosal ulcer: A case report.Semantic proximity Read ↗

Hemophagocytic lymphohistiocytosis: diagnosis, pathophysiology, treatment, and future perspectives.Semantic proximity Read ↗

Congenital neutropenia: diagnosis, molecular bases and patient management.Semantic proximity Read ↗

Different clinical phenotypes in familial severe congenital neutropenia cases with same mutation of the ELANE gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.