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Genetic profile in primary tumor tissue of advanced lung adenocarcinoma patients with adrenal metastasis.

Cancer genetics - 1 Jan 2025

Pan Haiqiao, Zhang Hongbin, Zhang Yongqian, Chen Xiaojing, Liu Zhai, Wu Yajing, Bai Na, Shi Yan, Zhao Min, Zhu Lingling

Abstract excerpt

The aim of this study was to examine the genomic characteristics and explore the molecular mechanisms underlying adrenal metastases in lung adenocarcinoma. 57 patients diagnosed with lung adenocarcinoma (LUAD) and adrenal metastases (AM) were enrolled, alongside 33 controls diagnosed with non-adrenal metastases (non-AM) at the time of diagnosis. The primary lung cancer tissue sample were analyzed using...

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PMID: 39673828
DOI: 10.1016/j.cancergen.2024.12.001

Genes

EGFR
KRAS
ALK
TNF
KEAP1
LRP1B
NOTCH1
RET
TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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